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Cytometric analysis of cell cycle distribution in 4T1 cells treated with 1.28 μM of Dtx in FABIO10 or a mixture of FA10 + BIO10 micelles: cell cycle phases (A), DNA fragmentation (B), changes in Annexin V/PI intensity (C), and cellular GSH (D). Data are expressed as mean values ± SD, ** p < 0.05.

Journal: Molecular Pharmaceutics

Article Title: Comparison of Micelles Single- and Dual-Targeted with Folic Acid and Biotin as the Delivery System of DocetaxelThe Influence of the Type and Amount of the Ligand on Morphology, Physicochemical Properties, and Cytotoxicity

doi: 10.1021/acs.molpharmaceut.5c00215

Figure Lengend Snippet: Cytometric analysis of cell cycle distribution in 4T1 cells treated with 1.28 μM of Dtx in FABIO10 or a mixture of FA10 + BIO10 micelles: cell cycle phases (A), DNA fragmentation (B), changes in Annexin V/PI intensity (C), and cellular GSH (D). Data are expressed as mean values ± SD, ** p < 0.05.

Article Snippet: All the cytometric analyses were performed using the NucleoCounter NC-3000 fluorescence imaging cytometer (ChemoMetec) and NucleoView NC-3000 software (version 2.1.25.12).

Techniques: